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Smoking significantly exacerbates this risk, with recent evidence showing that cigarette smoking is associated with a 22% increased risk of CVD events in MASLD patients compared to non-smokers (aHR 1.22, 95% CI 1.151.30) [71]

By reducing 8-OHdG, Epitalon may contribute to neuroprotection at the genomic level, preserving both structural integrity and functional longevity of neurons

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Researchers have also reported no significant negative effects on standard organ-function markers in short-term dosing

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