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Farxiga (dapagliflozin) is one of the most well-known pharmaceuticals in the SGLT2 inhibitor class, which is one of the more recent pharmacological classes for treating Type 2 diabetes
However, there are significant molecular differences between mice and humans in tight junction proteins and some transporters (Urich et al., 2012
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the definition of this profile showed a good level of homogeneity (mean inter-item Spearman 0.25) [41] and has been extensively described previously as belonging to the immuno-metabolic depression (IMD) domain, based on previous findings on individual symptoms with immuno-metabolic dysregulation [2]
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