Back to Journals Diabetes, Metabolic Syndrome and Obesity Volume 19 Gastrointestinal Adverse Effects of GLP-1 and Dual GLP-1/GIP Receptor Agonists: A Comprehensive Update in Diabetic and Obese Populations Authors Ylmaz N , Bastemir M Received 27 November 2025 Accepted for publication 13 January 2026 Published 30 January 2026 Volume 2026:19 584175 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 4 Editor who approved publication: Dr Halis Akturk Nimet Ylmaz, 1 Mehmet Bastemir 2 1 Department of Gastroenterology, SANKO University Faculty of Medicine, Gaziantep, Turkey
Discussion It has been widely accepted that class B1 GPCRs adopt a two-step model for ligand binding and receptor activation 34,43
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Phytase Phytase breaks down phytic acid (phytate), a storage form of phosphorus in grains, legumes, nuts, and seeds that can bind minerals like iron and zinc and reduce their absorption.36 Humans and other monogastric animals (single-chambered stomachs) have limited endogenous phytase activity, which is why phytase is widely used in animal feed and food processing to unlock more phosphorus and minerals.37 Human data, while smaller, points in the same direction
Nitazoxanide inhibits paramyxovirus replication by targeting the Fusion protein folding: role of glycoprotein-specific thiol oxidoreductase ERp57
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