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In a mouse model of RIRI, SeNP pretreatment reduced serum creatinine and blood urea nitrogen levels, alleviated tubular necrosis and inflammatory infiltration, and inhibited the elevation of ferroptosis marker ACSL4 and the decrease of GPX4, ultimately improving renal dysfunction and renal tissue structural damage [91]

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Arzneimittelforschung 33, 14461450

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