It is a synthetic 39-amino-acid molecule that activates three metabolic receptors GIP, GLP-1, and glucagon through one compound
Bleeding events related to SSRIs and SNRIs use have ranged from ecchymoses, hematomas, epistaxis, and petechiae to life-threatening hemorrhages
Some patients describe it similarly to a metallic taste in mouth Mounjaro, especially during rapid or early weight loss phases
Both formulations are manufactured by Eli Lilly and can be obtained through: Primary care physicians Endocrinologists Weight management specialists Telehealth weight loss clinics Compounding pharmacies (compounded tirzepatide versions) Insurance coverage varies widely
Oral semaglutide (Wegovy pill) is another alternative, though it only activates the GLP-1 receptor, not both GIP and GLP-1
doi:10.1111/j.1749-6632.1989.tb14973.x