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The reduced thymosin alpha-1 levels correspond to measurable impairment in regulatory T cell function, and regulatory T cell dysfunction is a recognized driver of psoriasis pathology

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Les protocoles prcliniques rapports dans la littrature documentent des concentrations typiques de 10 1 000 nM dans les modles de mlanocytes B16-F10 et MNT-1 pour tudier la cascade cAMP/PKA/MITF/tyrosinase