The most common side effects upon administration are nausea, diarrhea, vomiting, abdominal pain, and decreased appetite
33 To date, the medical literature does not clearly demonstrate differential effects of short- versus long-acting GLP-1 RAs on small or large-bowel motility, as most pharmacodynamic differences appear to be confined to gastric emptying
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Interestingly, exendin 2029, a fragment of exendin 939, directly and specifically inhibits transient receptor potential vanilloid 1 (TRPV1) activity in sensory neurons, thereby alleviating pain behaviors [28]
Lttl says compounds are not typically covered
These meta-analyses were more comprehensive, incorporating a larger number of studies, featuring more recent publications, and demonstrating greater statistical power compared to previous meta-analyses