By activating both GIP and GLP-1 receptors, Mounjaro enhances insulin secretion in response to meals, suppresses glucagon release, slows gastric emptying, and reduces appetiteleading to improved glycaemic control and significant weight loss
This is convenient for the patient and practitioner as we dont want to have to bother with discontinuation and dose titration if we dont have to
2017 Aug;56(8):815-823
Furthermore, these GLP-1RA medications have also been related to a reduction of neuroinflammation, probably due to its possible role in neuronal insulin signaling pathway restoration (49, 67, 68)
If fatigue persists beyond 412 weeks or disrupts your life, consult your doctor
In a safe switching between GLP-1 medications, stopping your current treatment and waiting the usual 7 days between injections is necessary