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A group of around 500 continued onto an extension trial that ended 104 weeks after baseline measurements

[42] [43] Other enzymes capable of producing superoxide are xanthine oxidase, NADPH oxidases and cytochromes P450

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SA--gal staining demonstrated a notable reduction in the number of SA--gal-positive cells post-FOXO4-DRI treatment compared to the PBS group (Figure 4D)

Maybe a vague sense of fullness that was not there before