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These rare Class I G6PD variants are extremely heterogeneous with respect to biochemical kinetics, but have in common very low in vitro activity and/or marked enzyme instability

Structural and functional characterization of the mutant Escherichia coli glutaredoxin (C14S) and its mixed disulfide with glutathione

Additionally, patients in the NAC group experienced significant improvements in Parkinsons symptoms

(2020) reported that irisin activates the Nrf2 pathway, which is known to regulate proteasomal function and oxidative stress responses, potentially contributing to reduced protein aggregation 33

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