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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

Diabetes Res Clin Pract 2022

Due to the long duration of diabetes, T2D patients have higher risks of macrovascular and microvascular damage, as well as other severe complications, such as diabetic nephropathy, diabetic cardiomyopathy, non-alcoholic fatty liver disease (NAFLD), diabetic retinopathy, cognitive impairment, that cause mortality (Gregg et al., 2014)