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Yan Z, Dai Y, Fu H, Zheng Y, Bao D, Yin Y, et al

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Succinate is an inflammatory signal that induces IL-1 through HIF-1

Meanwhile, the traditional managers of drug benefits, like pharmacy benefit management companies, are under fire for a lack of transparency in how they make money, with many of them eliminating controversial rebates they are paid by drug makers or working to scale them back to give their clients a bigger discount on prescription drugs

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