Novo Nordisk announced that the US Food and Drug Administration (FDA) has approved once-daily Wegovy pill, the first oral GLP-1 medicine for obesity in the US.3 Wegovy pill is used with a reduced calorie diet and increased physical activity for adults with obesity, or with overweight who also have weight-related medical problems, to help them lose weight and keep it off.3 Wegovy pill is also indicated to reduce the risk of major adverse cardiovascular events (MACE) such as death, heart attack, or stroke in adults with overweight or obesity and established cardiovascular disease
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The FDA warned earlier this year that some compounding pharmacies were using improper base ingredients to compound semaglutide
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The study authors themselves concluded that these findings "provide reassurance that a greater proportion of lean mass is not lost with retatrutide despite the overall increased weight loss." When researchers who designed the trial reach that conclusion, it carries significant weight
Conflict of interest GYW has been Editor-in-Chief of Journal of Clinical and Translational Hepatology since 2013