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DOI: 10.1083/jcb.201608123 Cheerathodi, M

The drugs, which work by slowing the digestive tract, thus tamping down hunger signals, can be incredibly helpful and even life-saving for people with certain medical conditions but are commonly prescribed off-label for rapid weight loss

I outline a way to play the picks and shovels of this issue, but it is also indicative of the fact that there is significant demand and further impact to be had for this theme - simply put, not enough people are on it yet

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Mitigation strategies include administering the injection on an empty stomach, using ginger or ondansetron 30 minutes before dosing, and reducing the dose by 3040% temporarily

The concomitant administration of -tocotrienol has demonstrated an increased efficacy of gemcitabine (88), and a phase I study on pancreatic cancer patients was conducted with escalating doses of -tocotrienol in the 2 weeks before surgery (91)