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Increased P85alpha is a potent negative regulator of skeletal muscle insulin signaling and induces in vivo insulin resistance associated with growth hormone excess

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It is because tissue repair is multifactorial

Concomitant use with coumarin anticoagulants such as warfarin has been associated with elevations in the international normalized ratio, requiring closer INR surveillance and potential dose adjustment

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So it makes a lot of sense to ban them