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The inability of megakaryocytes to mature properly results in thrombocytopenia

Methods Experimental model and details Animal studies All animal studies were performed according to protocols approved by the University Committee on Animal Resources at the University of Rochester Medical Center

Aya Yamada (Saga University) for her assistance with this work

Targeting GSTP1-1 induces JNK activation and leads to apoptosis in cisplatin-sensitive and -resistant human osteosarcoma cell lines

Recovery requires tissue repair, inflammation control, and growth factor activation working together

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