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The nasal spray route for PT-141 Spray research offers an important pharmacokinetic advantage for laboratory protocols: transmucosal absorption bypasses first-pass hepatic metabolism, delivering the peptide directly to systemic circulation with rapid onset
Glutamate-induced over-expression of GAD is down-regulated by acetyl-L-carnitine in rat islet cells
PMID 1330133
Lancet 395 , 565574 (2020)
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