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Cindy Wassef, a dermatologist at Premier Health Associates in Randolph, N.J

Diagnosis of other severe psychiatric disorder (for example, schizophrenia, bipolar disorder)

Tirzepatide , on the other hand, is a twincretin , activating both GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors

Women planning pregnancy should discontinue use at least 2 months before attempting conception to allow for complete medication washout

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This is not a formal ceiling because no FDA-approved limit exists, but it represents the upper range of what is supported by preclinical scaling and provider experience