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A comparison of 119 patients suffering from AD with 267 controls found that alterations in serum BAs correlate with cerebrospinal fluid (CSF) A142, tau, and p-tau
Patients on 7 days per month metronidazole therapy had normalized TMAO levels (PAT12-14), whereas two patients on 5 days per month metronidazole therapy had extreme TMAO elevations (PAT 17-18) suggesting that the duration of antibiotic therapy may impact microbial l-carnitine degradation (Table 1)
Its antioxidant properties are particularly notable as it has the capability to regenerate other antioxidants, such as vitamins C and E, which are essential for skin health
At the same time, it slows down the rate at which food leaves the stomach and reduces appetite by acting on appetite centers in the brain
These provide reference points for comparison