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Appendix 1
Skin and Other Effects: Very rarely, severe skin rashes or abdominal pain have been reported
You should contact your clinician if: Appetite returns sharply Weight increases beyond your agreed maintenance range You regain 5 to 10 pounds Side effects affect eating, hydration, or activity You are considering stopping, restarting, tapering, spacing, or changing GLP-1 medication You feel out of control with cravings or binge episodes You have persistent vomiting, severe abdominal pain, dehydration, or concerning symptoms You are pregnant, planning pregnancy, or have a new diagnosis or medication You need updated lab work, metabolic testing, or nutrition targets The safest maintenance plan is proactive, not reactive
The newly revamped drink, called Update, uses paraxanthine to deliver "smooth, steady energy without the jitters, crashes, or sleep disruption commonly associated with traditional energy drinks. The company also claims the drink contains "zero sugar, zero calories and zero artificial flavours or colours." Caffeine without the crash Paraxanthine is a naturally occurring compound produced when the body metabolises caffeine
ElSayed NA, Aleppo G, Aroda VR, Bannuru RR, Brown FM, Bruemmer D, et al
