Sag CM, Santos CXC, Shah AM
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Preliminary data from a phase 1b extension study (NCT05292911) involving 64 individuals with MRI-PDFF 10% and BMI 28 kg/m 2 demonstrated that 50%, 44%, and 60% of participants presenting baseline alanine aminotransferase (ALT) 30 IU/L reached combined MRI-PDFF reduction 30% and ALT reduction 17 IU/L at pemvidutide doses of 1.2, 1.8, and 2.4 mg, respectively, vs
10 The SURMOUNT-1 trial demonstrated weight loss of 15-21% after 72 weeks of tirzepatide (5, 10 or 15 mg)
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