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Some observational research has found a possible association between taking semaglutide (like Ozempic) and a higher risk of gastroparesis and other gastrointestinal complications

Colleagues and peers remember him being close to tears at meetings in Europe when no one showed interest in licensing his Gila peptide

Still, there was an intriguing wrinkle

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What the clinical evidence shows Several large, peer-reviewed studies have quantified the risk: The STEP 1 trial (NEJM, 2021): patients on high-dose semaglutide lost an average of 14.9% of their body weight over 68 weeks

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