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Significant differences in RQ were observed at several time points (e.g., 3 min ( p = 0.039), 5 min ( p = 0.017, r = 0.67), 7 min ( p = 0.027)) when L-carnitine was consumed, highlighting that the supplementation led to increased fat oxidation and decreased carbohydrate reliance, especially during the early and middle phases of exercise

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As a result, when neuroglial metabolic integrity is intact, glutamate and GSH levels remain tightly linked in the brain

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Informing patients on potential side effects, gradual dose escalation, and contraindications is essential to ensure safety and adherence

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