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Dysfunction of GPX4, often due to glutathione depletion, renders cells vulnerable to ferroptosis

However, older adults, those on certain medications or with gastrointestinal issues, and people who follow a plant-based diet may be more at risk of deficiency

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This was demonstrated in a study which noted that rescue morphine was used more frequently in patients with lower APAP concentrations ( Differences in APAP efficacy among pediatric and adult populations were also observed

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