They should also seek to identify patient subgroups that may benefit the most, such as those with low baseline carnitine levels or undertaking certain procedures like PCI/CABG, evaluating safety and interactions with guideline-directed therapies
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References : Merck Manual UpToDate
"In vitro and in vivo inhibition of human flavin-containing monooxygenase form 3 (FMO3) in the presence of dietary indoles"
Lipoic acid (LA), a well-known antioxidant, has been reported to exert the protective effect on I/R-induced AKI by scavenging ROS (Bae et al., 2009)