Many apparent stalls are simply someone still early in the ladder expecting a maintenance-level effect
Regular physical activity helps preserve lean muscle mass during weight reduction, which is particularly important since approximately 25% to 40% of weight lost with GLP-1 agonists alone may come from lean tissue rather than fat, according to body composition studies
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While most nausea from GLP-1 therapies is self-limited, serious adverse events such as pancreatitis, severe dehydration, or gallbladder disease require immediate attention and possibly discontinuation of the medication
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Caregivers should still maintain the fasting window for levothyroxine