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Therefore, SAM level changes after hemin or DMF treatment may affect CBS expression as well

Subjects provided written informed consent after verbal explanation of all study procedures, in accordance with the Institutional Medical Sciences Subcommittee for the Protection of Human Subjects

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[9] C S Johnston, C G Meyer, J C Srilakshmi, Vitamin C elevates red blood cell glutathione in healthy adults, Am J Clin Nutr

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Consequently, untreated patients develop neurocognitive deficits (Rausell et al., 2019), as well as psychiatric, behavioral and movement disorders that become more evident as the child grows (Blau et al., 2010