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Osmotic pump implantation On Day 0, all mice were implanted subcutaneously with an Alzet Model 2004 minipump, where the stainless-steel cannula was replaced with PEEK tubing (DURECT Corporation, Cat# 0002496) to allow for further body composition scanning

Visible lumps of scar tissue and disrupted fat architecture

SS-31 targets cardiolipin in the mitochondrial membrane, stabilizing it and enhancing ATP production, which improves energy production and muscle function, particularly in patients with mitochondrial myopathy