Discuss your reasons for wanting to switch, any side effects you may be experiencing on Semaglutide, and your goals for weight loss or diabetes management
While GLP-1R agonists are already established in metabolic disease, their expression in immune cells opens new avenues for mechanistic research
[54] in women with PCOS, BMI 25 kg/m 2 and/or insulin resistance, treatment with liraglutide 1.8 mg/day for 26 weeks, along with a higher weight loss, induced significant reductions in fasting plasma glucose, HbA1c, and plasma glucose AUC, whereas Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), Matsuda index and insulin AUC remained unchanged
7 and 8
Ask a clinician who knows your medical history if a GLP-1 could benefit you
NHS access would come later