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Mounjaro/Zepbound (tirzepatide), approved dual GLP-1/GIP agonist for type 2 diabetes and obesity Recent Highlights: In April 2026, the FDA approved orforglipron (Foundayo), making it one of the first oral GLP-1 pills that can be taken any time of day and that has no food or water restrictions

So, typically the more effective the medication, the more likely the risk of adverse events

The grand effect of these actions: taking in less calories due to feeling satiated earlier and for longer

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Use the 3-bite rule on the hardest days

Evidence from German clinical practice in an IQVIA study underscores this gap: BMI documentation was recorded for only 10.8% of patients [2] highlighting that comprehensive measurements of obesity are not being translated to clinical practice