At the end of the study, the authors observed improved dermal density, reduced periorbital wrinkles, and skin smoothness in the treatment group
Read More: Physician-Supervised Weight Loss Program Potential Risks and Side Effects Like any medication, weight loss medications come with potential risks and side effects that should be carefully considered before starting treatment
The honest framing: this isn't a fountain of youth, but for the right person it can help the body do more of what it did naturally when you were younger better sleep, better recovery, and a leaner, stronger baseline as part of a deliberate, monitored plan rather than a quick fix
Others get denied at 35
Topical effects Most reported topical effects are mild and local: redness, tingling, dryness, or transient irritation at the application site, typically more common with concentrations above 4%
For example, a 2023 study in the UK found that 57% of adults attributed being overweight primarily to a lack of willpower (Beeken and Wardle, 2013)