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"Role of N -acetylcysteine in the management of COPD"

Furthermore, such a retrospective design inherently limits the identification of causal relationships, and unmeasured residual confounding variablessuch as glycemic control, hypoglycemic episodes, familial suicide history, and socioeconomic statusmay persist

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418 Findings from one observational study suggested the effect is small: the study analyzed data from 2,295 male participants in the NHANES and found each hour less of sleep was correlated with a 5.85 ng/dL decrease in total testosterone