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Studies following patients after stopping GLP-1 therapy show weight regain within about 18 months without sustained lifestyle changes
A.Di ChiroG
Problematisch: Der Verlust der Schutzfunktion von Glutathion erhht zwangslufig den oxidativen Stress, was sich wiederum negativ auf den Alterungsprozess auswirkt
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Similar effects have been demonstrated in osteoarthritis models, where liraglutide facilitates macrophage polarization toward the anti-inflammatory M2 phenotype by downregulating M1-associated markers such as Mcp-1 and Cd38, while upregulating M2-related genes including Erg-2, reducing the secretion of pro-inflammatory cytokines and mitigates inflammatory responses (Meurot et al., 2022)
Ikeno, Y., Bronson, R
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