This work was also supported by the National Key Research and Development Program of China (2018YFA0507001, 2018YFA0507000, 2018YFA0508100), the National Natural Science Foundation of China grants 31770898 (G.S.), 31900895 (L.Y.) and 81872915 (M.-W.W.), the National Science and Technology Major Project Key New Drug Creation and Manufacturing Program of China (2018ZX09735-001) and China Postdoctoral Science Foundation (2017M622365)
PubMed CrossRef Insel BJ, Schaefer CA, McKeague IW, et al

Needle sizes most commonly used at the RCH include: 25g x 25mm ORANGE 23g x 25mm BLUE 21g x 38mm GREEN Equipment Appropriate size needle for administration Drawing up needle and syringe (if medication not pre-filled) Sharps container Alcohol impregnated swab (if area visibly soiled) Cotton ball Band-Aid (check for allergies) Personal Protective Equipment (PPE) for hazardous medications or infectious patients The procedure Prepare patient and obtain consent Perform the five moments of hand hygiene Prepare equipment as per Aseptic Technique Complete the six rights of medication administration Don PPE if required (particularly for hazardous medications) Draw up or prime medication as per Paediatric Injectable Guidelines Position patient in a safe and comfortable position Procedure Management Guideline Consider the use of comfort techniques such as distraction, buzzy bee, ice or a countdown Landmark injection site (see above) Clean site with an alcohol swab (if required) Stretch the skin flat (Z-tracking if applicable) Inject the needle to the hub at a 90-degree angle Do not aspirate or drawback as this can increase pain and discomfort in children Inject the medication at a slow and steady pace Remove the needle and apply a cotton ball Place the needle in a sharps container Apply Band-Aid Remove PPE (if required) Perform the five moments of hand hygiene Special considerations Monitor for immediate adverse reactions, e.g., fever, rash, vomiting, shortness of breath

Get it wrong, and you could compromise the integrity of your entire experiment, leading to inconsistent data and wasted resources
Claessen, J
But we can look at their tirzepatide savings program as a probable model for what retatrutide support will look like post-approval