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Furthermore, during follow-up, only minimal changes were observed between baseline and the end of the trial in the concurrent use of antihypertensive and lipid-lowering medications, and these changes were comparable between groups

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Also, further extensive studies on regulation of HIF-1 expression (such as heat shock protein 90, HSP90), and specific targeting of certain transcriptional activation of certain HIF-1 target genes (Minet et al., 1999

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