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Glutathione conjugation as a mechanism for the transport of reactive metabolites

Response rates to single-agent chemotherapy after exposure to immune checkpoint inhibitors in advanced non-small cell lung cancer

We found that wild-type MZB were more susceptible to Gclc inhibition as shown by a stronger BSO concentration-dependent decrease in viability and total immunoglobulin secretion in the culture supernatants when compared to FoB (Fig