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Some options may have contraindications, require clinician supervision, and may cause side effects

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These modifications enhance its half-life by increasing albumin binding and inhibiting degradation by DPP-4, allowing for once-weekly dosing

Even if shots dont bother you, oral medications can be more convenient than GLP-1 injectables: Pills are easy to pack and store and dont require careful needle or pen disposal

Ribas V et al

Most patients tolerate insulin therapy without significant GI complaints