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These pathways have become a focal point for translational oncology research, these interconnected mechanisms are summarized in Figure 1
Furthermore, in both of our structures, TM7 shifts towards TM6 compared to that in the inactive GHSR, closing the previously observed crevasse in the inactive structure (see Discussion below)
Immunoblotting Anti-GFP (Roche, 11814460001), anti-Pgk1 (OriGene EU, AP21371AF-N), anti-mouse IgG-hrp (GE Healthcare, NA931V), and anti-rabbit IgG-hrp (GE Healthcare, NA934V) antibodies were purchased
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