According to FDA labeling, these medications are not recommended for patients with severe gastrointestinal disease, including severe gastroparesis, as they may worsen symptoms
Though testing is always needed before extrapolating animal dosing to human dosing, this 5mg/kg dose is approximately equivalent to 0.4mg/kg in humans based on human equivalent dose calculations provided by the FDA
Prescribing Information: Glucophage (metformin hydrochloride) tablets
Directions were obvious and simple to understand to preform
Copper is only required in trace amounts by the body, and too much copper buildup could theoretically cause nausea, abdominal pain, tiredness, liver damage, and neurological effects
doi: 10.1053/j.gastro.2006.11.002