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Native IGF-1 is heavily bound by IGFBPs in serum, which limits free activity
Sachan DA, Rhew TH
These findings argue against the notion that GIP co-agonism reduces the risk of adverse GI events
Together, these findings indicated the role of TGF/SMAD signalling in the induction of pancreatic fibrosis
Laboratory research utilizes these structural insights to develop peptides with improved cellular uptake, enhanced selectivity, and reduced off-target effects, providing researchers with increasingly sophisticated tools for senescence research applications
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