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DOI: 10.2164/jandrol.108.005215 Disclaimer: This article is for informational purposes only and does not constitute medical advice

Subcutaneous administration suffers from: Lower bioavailability Variable absorption Different pharmacokinetics Which means the systemic exposure of DSIP via subcutaneous administration is not equivalent to what is achieved with intravenous infusion

6.3 Crosstalk between the glutathione and thioredoxin systems The glutathione (GSH/GR/GPx) and thioredoxin (Trx/TrxR/Prx) systems constitute the two primary thiol-based antioxidant defenses in cells

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"Unfortunately, there is a loophole which is being used and that is something that needs to be closed for the safety of patients," she said