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A shot will lose very little, if any
Higher-Caution Situations Extra medical supervision is important if you: have a history of reactions to injectable vitamins/cobalamins have significant kidney or liver disease are pregnant or breastfeeding are offered a compounded MIC B12 product without clear labeling of ingredients, concentrations, and compounding source The FDAs overview of compounding helps explain why quality can vary (see Compounding and the FDA: Questions and Answers )
(2018) used the current understanding from tendon, ligament and bone and applied this to gastrointestinal tract healing, which could provide a pathway for understanding of the systemic healing capabilities for applications to other tissues
While they are often marketed as a "miracle" alternative, the professional and clinical landscape also reveals a mix of robust lab-based evidence
However, check with your healthcare provider for accuracy