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Eventually, this may result in cell death from the destructive cellular programs

(More information) Subclinical deficiency (low status) of riboflavin without clinical signs may be widespread, including in high-income countries, but it usually goes undetected because riboflavin biomarkers are very rarely measured in human studies

What I found suggested that this wasnt merely an anecdote or internet folklore

Blood samples were immediately centrifuged, and plasma was transferred to pre-prepared tubes containing acetonitrile and an internal standard of Nle-YI-(6) aminohexanoic amide, 100 g/ml in isotonic saline

1 2 3 4 "ESA/SRE(2014)1 JUICE definition study report (Red Book)"

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