Some 120 drugs are now in clinical development for obesity, according to a recent report from Iqvia, from Wegovy mimics to psilocybin and coated glucose beads
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For example, some studies found that rapamycin, an inhibitor of mTOR, protected against neuronal injury through induction of autophagy in vivo 16,58,59
Restarting titration is only necessary if you have had a significant gap in therapy (typically 4+ weeks)
Knowing when your peaks and troughs occur lets you plan what to eat and when, rather than fighting against the pharmacokinetic tide