SCO also was shown to decrease the expression of TNF-, IL-6, IL-1 and Rela, increase the expression of krueppel-like factor 10 (Klf10), and attenuate lipid metabolism dysfunction and inflammation by activating the peroxisome proliferator-activated receptor (PPAR) signaling pathway (32)
Amyotroph Lateral Scler Frontotemporal Degener 21(5-6):373379
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The maximum dose produced the highest average results, but the incremental benefit over 10 mg was relatively modest, about 1.1 additional percentage points of body weight loss