glp 1 a1c lowering Mean reduction in clinical studies of GLP-1RA More data on Retatrutide dropped

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Chronic diarrhea persisting beyond four weeks, even if mild, requires investigation to exclude conditions such as microscopic colitis, bile acid malabsorption, or exocrine pancreatic insufficiency

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3 However, the active forms of GLP-1 have a very short plasma half-life (less than 2 minutes) due to rapid degradation by the enzyme dipeptidyl peptidase-4 (DPP-4)