Health and lifestyle information included smoking status (non-smoker vs current smoker), alcohol consumption as units per week, physical activity assessed using the International Physical Activity Questionnaire (IPAQ, expressed in Metabolic Equivalent Total (MET) minutes per week [46], and body mass index (BMI) measured during physical examination
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Eeyarestatin I stabilizes the p97/VCP complex, enhancing ERAD activity and reducing misfolded protein accumulation in HD and ALS models