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10.1016/0168-9452(95)04156-O 117 SatoY.MasutaY.SaitoK.MurayamaS.OzawaK
The study of drug metabolism is one of the tenets of pharmacokinetics (PK) as metabolism (M), the fourth stage of LADME (a drug's transit through the body), involves the enzymatic biotransformation and non-enzymatic biotransformation of a drug, thereby leading to the fifth stage, excretion (E)
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