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It must be noted, however, that increased GFAP expression and GFAP-positive astrocytic profiles are not always associated with pathology

An RCT of 174 patients with severe alcoholic hepatitis found that the combination of prednisolone + NAC (IV for 5 days, then oral for 2 weeks) significantly reduced 1-month mortality compared to prednisolone alone (8% vs 24%, p=0.006), though the difference was not significant at 6 months (Nguyen-Khac et al., N Engl J Med, 2011) [36]

GHK-Cu is widely used in cosmetics and considered well tolerated topically, but it is not a medical treatment

Accessed 4 Aug 2023

Retrieved 25 March 2007

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