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A 2024 randomized trial found that a single high dose reduced the decline in processing speed and memory during overnight sleep deprivation, with a smaller effect in rested people

Concentrations naturally decline with age (from about 200 ng/mL at age 20 to 80 ng/mL by age 60), which is part of why supplementation makes sense

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World J Psychiatry

MOTSc is a short research peptide made of 16 amino acids

It also promotes nerve regeneration after physical transection, meaning it does not just protect neurons from dying but actively supports the regrowth of damaged nerve fibers